Balskus

David A. Evans

FAS Memorial Minute for David Albert Evans, 81

February 27, 2024

At a meeting of the Faculty of Arts and Sciences on Feb. 6, 2024, the following tribute to the life and service of the late David Albert Evans was spread upon the permanent records of the Faculty.

David Albert Evans was one of the most influential organic chemists in the history of the field, and his impact was felt through his research, mentorship, and teaching.  He discovered practical and general ways to synthesize polyketides, a broad class of medicinally important natural products.  To crack this problem, he devised exquisitely simple yet broadly...

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New research: Vaginal bacteria must eat to survive — but how?

New research: Vaginal bacteria must eat to survive — but how?

August 15, 2023
Like the human gut, the female genital tract is its own complex microbial ecosystem, where billions of beneficial bacteria make their home. The way Harvard chemist Emily Balskus sees it, the vaginal microbiome is an underappreciated, understudied part of the body where critically important chemistry takes place.

The Thomas Dudley Cabot Professor of Chemistry and a Howard...

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CCB celebrates 2nd annual HSLS cohort

CCB celebrates 2nd annual HSLS cohort

August 21, 2023

The Harvard Department of Chemistry and Chemical Biology has wrapped up its second annual High School Lab Skills summer intern program, providing an immersive learning experience for a group of local high school students to experience the world of cutting-edge research. The department celebrated the success of the program with a breakfast event on August 17 that highlighted and honored commitment of all its participants.

For six weeks, a cohort of talented and motivated Brighton-llston High...

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CCB kicks off 2nd annual High School Lab Skills Summer Research Program

CCB kicks off 2nd annual High School Lab Skills Summer Research Program

June 12, 2023

On June 1st, CCB kicked off the second annual High School Lab Skills Summer Research Program with “Match Day” at the Harvard Ed Portal in Allston. The afternoon highlighted the work of the six Brighton-Allston High School students enrolled in the program and provided an opportunity for CCB program staff, graduate and postdoc mentors, Ed portal staff and Brighton-Allston high school science teachers to meet and celebrate the work of this program. The high school students were handed a letter which contained their highly anticipated summer lab placement assignments. Once the matches were...

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A headshot of Emily Balskus

How E. coli bacteria activate a toxin they produce in a way that avoids self-harm

October 18, 2022

The microorganisms living in, on, and around us, collectively known as the microbiome, produce metabolites that affect our health. Some of these molecules are essential for our wellbeing, while others can harm us. Colibactin is an example of a toxin, produced as part of microbial warfare, which induces double-stranded breaks in the DNA of cells in the intestinal epithelium and is correlated with higher incidences of diseases such as colorectal cancer.

Bacteria producing colibactin must protect their own DNA, so they assemble a non-toxic precursor (precolibactin) in their...

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